Hi kbro,
I have been meaning to investigate this further for ages so thanks for the prompting.
I have a Dream Guiplug with a Mimo Monster attached and working, an Imo Pivot attached to the 2nd USB and two Mimo 720S monitors attached to the Hub output on the Monster.
There are now devices /dev/fb0 to /dev/fb3 created. fb0 is the Gnome desktop and fb1-3 are the monitors which I can dump an image to any of these and it's displayed.
By default if I touch any of the screens the mouse pointer is moved on the Gnome Desktop.
This was using the Dreamplug with GuiPlug v2.6 and no configuration changes.

NewITJames